文献类型: 外文期刊
作者: Huang, Daye 1 ; Zhang, Zhigang 1 ; Li, Yanyan 3 ; Liu, Fang 1 ; Huang, Wenbo 1 ; Min, Yong 1 ; Wang, Kaimei 1 ; Yang, Jingzhong 1 ; Cao, Chunxia 1 ; Gong, Yan 1 ; Ke, Shaoyong 1 ;
作者机构: 1.Hubei Acad Agr Sci, Natl Biopesticide Engn Res Ctr, Hubei Biopesticide Engn Res Ctr, Wuhan 430064, Peoples R China
2.Minist Agr & Rural Affairs, Key Lab Microbial Pesticides, Wuhan 430064, Peoples R China
3.Tobacco Res Inst Hubei Prov, Wuhan 430030, Peoples R China
关键词: Carboline alkaloids; Carboline derivatives; Antifungal activity; Broad-spectrum
期刊名称:PHYTOCHEMISTRY LETTERS ( 影响因子:1.873; 五年影响因子:1.875 )
ISSN: 1874-3900
年卷期: 2022 年 48 卷
页码:
收录情况: SCI
摘要: Carboline alkaloids are a class of important heterocyclic natural products, which usually present extensive bioactivities. During the course of our research for active compounds from natural products, the pityriacitrin and pityriacitrin B belonged carboline alkaloids have been isolated from a Chinese Burkholderia sp. NBF227, which indicated potential antifungal activities. So, in order to develop these carboline alkaloids as potential fungicidal agents, a series of pityriacitrin derivatives were investigated for their antifungal activities against Phytophthora capsici, Sclerotinia sclerotiorum, Botrytis cinerea and Rhizoctonia solani, and the results demonstrated that com-pounds 4, 10 and 19 displayed broad-spectrum antifungal activities. In addition, in vivo bioassay also indicated that compounds 4 and 10 could protect the pepper leaves and grape fruits against infection by P. capsici and B. cinerea, respectively. The possible mechanism of antifungal action for these compounds was also explored.
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