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Study on the Therapeutic Effect of Modified Yujin Powder on E. coli in the Procapra przewalskii

文献类型： 外文期刊

作者： Song, Chunjie 1 ; Gan, Shangquan 2 ; Shen, Xiaoyun 1 ;

作者机构： 1.Southwest Univ Sci & Technol, Sch Life Sci & Engn, Mianyang 621010, Sichuan, Peoples R China

2.Xinjiang Acad Agr & Reclamat Sci, State Key Lab Sheep Genet Improvement & Hlth Prod, Shihezi 832000, Xinjiang, Peoples R China

3.World Bank, Poverty Alleviat Project Off Guizhou, Guiyang 550004, Peoples R China

关键词： The E; coli; The P; przewalskii; Modified Yujin powder; Gentamicin sulfate; Blood parameter

期刊名称：PAKISTAN JOURNAL OF ZOOLOGY （ 影响因子：0.687； 五年影响因子：0.736 ）

ISSN： 0030-9923

年卷期： 2022 年 54 卷 2 期

页码：

收录情况： SCI

摘要： This experiment was to study the therapeutic effect of modified Yujin powder on E. coli in the P. przewalskii. Twenty the Procapra przewalskii with the E. coli were selected from the Wildlife Rescue Center of the Qinghai Lake National Nature Reserve and randomly divided into low-dose group, high -dose group, gentamicin sulfate group and control group with 5 Procapra przewalskii in each group. The P. przewalskii in modified Yujin powder group were given Yujing powder once every morning and evening, 3, 4 mL/ (kg??BW) for the low-dose group and high-dose group, respectively. The P. przewalskii were injected with gentamicin sulfate intramuscularly,once every morning and evening. The P. przewalskii in control group were fed normally and no medicine was given. After 7 d, the clinical symptoms of the P. przewalskii were observed, and the blood routine, serum biochemical parameter, serum immune and antioxidant indices were measured. The results showed that the P. przewalskii were sensitive reaction, increased appetite, and no diarrhea in the modified Yujin powder group. The healing rates were 75%, 85%, and 60% in low-dose group, high-dose group, gentamicin sulfate group, respectively. The effects of modified Yujin powder was better than gentamicin sulfate. The contents of blood urea nitrogen (BUN), malondialdehyde (MDA), and the number of white blood cell (WBC) in 3 drug delivery groups were extremely significantly lower (P<0.01) than the control group, and the contents of potassium (K), total protein (TP), albumin (ALB), globulin (GLB), and total antioxidant capacity (T-AOC) in the 3 drug delivery groups were extremely significantly higher (P<0.01) than that of control group, but there were no remarkable differences between the 3 drug delivery groups. The serum catalase (CAT) activity in the high-dose group was extremely significantly higher (P<0.01) than that in the low-dose group, gentamicin sulfate group, and control group. Consequently, modified Yujin powder had a good therapeutic effect on the E. coli in P. przewalskii, and the effect of the high-dose group was better.

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