Investigation of potential genetic factors for growth traits in yellow-feather broilers using weighted single-step genome-wide association study
文献类型： 外文期刊
作者： Fang, Xiang 1 ; Ye, Haoqiang 1 ; Zhang, Siyu 1 ; Guo, Lijin 1 ; Xu, Yibin 1 ; Zhang, Dexiang 1 ; Nie, Qinghua 1 ;
作者机构： 1.South China Agr Univ, State Key Lab Livestock & Poultry Breeding, Guangzhou 510642, Peoples R China
2.South China Agr Univ, Lingnan Guangdong Lab Agr, Guangzhou 510642, Peoples R China
3.Guangdong Prov Key Lab Agroanim Genom & Mol Breedi, Guangzhou 510642, Peoples R China
4.South China Agr Univ, Key Lab Chicken Genet Breeding & Reprod, Minist Agr & Rural Affair, Guangzhou 510642, Peoples R China
5.Shaoguan Univ, Henry Fok Sch Biol & Agr, Shaoguan 512005, Peoples R China
关键词： yellow-feather broiler; wssGWAS; pedigree; QTL; growth traits
期刊名称：POULTRY SCIENCE （ 影响因子：4.4； 五年影响因子：4.4 ）
ISSN： 0032-5791
年卷期： 2023 年 102 卷 11 期
页码：
收录情况： SCI
摘要： Yellow-feather broilers take a large por-tion of poultry industry in China due to its meat charac-teristics. Improving the growth traits of yellow-feathered broilers will have great significance for the Chinese poul-try market. The current study was designed to investigate the potential genetic factors using the weighted single-step genome-wide association study (wssGWAS) method, which takes consideration of more factors includ-ing pedigree, sex, environment and has more accuracy than traditional GWAS. The yellow-feather dwarf chick-ens from Wens Nanfang Poultry Breeding Co. Ltd. were revolved to recode 9 growth traits: Average daily gain (ADG), body weight (BW) at 45 d, 49 d, 56 d, 63 d, 70 d, 77 d, 84 d, 91 d for analysis. For the results, the region 4.63 to 5.03 Mb on chromosome 15, which was the QTL overlapped in BW45, BW49, BW56, BW63, BW84, might be the crucial genetic region for growth traits. Seven GO terms and 3 KEGG pathways, GO:0005200, GO:0005882, GO:0045111, GO:0099513, GO:0099081, GO:0099512, GO:0099080, KEGG:gga04020, KEGG: gga04540, KEGG:gga04210, were detected to relevant with growth traits. The genes enriched in these biological processes (NRAS, TUBB1, ADORA2B, NTRK3, NGF, TNNC2, F-KER, LOC429492, LOC431325, LOC431324, LOC396480) might have the function in growth of yellow-feather broilers.
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