文献类型： 外文期刊
作者： Wang, Kun 1 ; Wang, Jun 2 ; Zhu, Chenglong 1 ; Yang, Liandong 5 ; Ren, Yandong 1 ; Ruan, Jue 6 ; Fan, Guangyi 7 ; Hu, Jia 1 ;
作者机构： 1.Northwestern Polytech Univ, Sch Ecol & Environm, Xian 710072, Peoples R China
2.South China Agr Univ, Coll Marine Sci, Joint Lab Guangdong Prov & Hong Kong Reg Marine B, Guangzhou 510642, Peoples R China
3.Hubei Univ Technol, Sch Civil Engn Architecture & Environm, Wuhan 430068, Peoples R China
4.Chinese Acad Sci, Kunming Inst Zool, State Key Lab Genet Resources & Evolut, Kunming 650223, Yunnan, Peoples R China
5.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China
6.Chinese Acad Agr Sci, Agr Genom Inst Shenzhen, Guangdong Lab Lingnan Modern Agr, Genome Anal Lab,Minist Agr, Shenzhen 518120, Peoples R China
7.BGI Qingdao, Qingdao 266555, Peoples R China
8.BGI Shenzhen, Shenzhen 518083, Peoples R China
9.Grand Biosci, Beijing 102200, Peoples R China
10.Chinese Acad Sci, Inst Vertebrate Paleontol & Paleoanthropol, Beijing 100044, Peoples R China
11.Northwest A&F Univ, Coll Vet Med, Dept Clin Vet Med, Key Lab Anim Biotechnol,Minist Agr, Yangling 712100, Shaanxi, Peoples R China
12.Chinese Acad Sci, Beijing Inst Genom, Beijing 100101, Peoples R China
13.China Natl Ctr Bioinformat, Beijing 100101, Peoples R China
14.Southwest Univ, Sch Life Sci, Key Lab Freshwater Fish Reprod & Dev, Chongqing 400715, Peoples R China
15.Chinese Acad Sci, Ctr Excellence Anim Evolut & Genet, Kunming 650223, Yunnan, Peoples R China
16.Univ Copenhagen, Villum Ctr Biodivers Genom, Dept Biol, Sect Ecol & Evolut, Copenhagen, Denmark
17.Chinese Acad Sci, Inst Deep Sea Sci & Engn, Sanya 572000, Peoples R China
18.Northwestern Polytech Univ, Xian 710072, Peoples R China
期刊名称：CELL （ 影响因子：38.637； 五年影响因子：38.62 ）
ISSN： 0092-8674
年卷期： 2021 年 184 卷 5 期
页码：
收录情况： SCI
摘要： Lungfishes are the closest extant relatives of tetrapods and preserve ancestral traits linked with the water-to-land transition. However, their huge genome sizes have hindered understanding of this key transition in evolution. Here, we report a 40-Gb chromosome-level assembly of the African lungfish (Protopterus annectens) genome, which is the largest genome assembly ever reported and has a contig and chromosome N50 of 1.60 Mb and 2.81 Gb, respectively. The large size of the lungfish genome is due mainly to retrotransposons. Genes with ultra-long length show similar expression levels to other genes, indicating that lungfishes have evolved high transcription efficacy to keep gene expression balanced. Together with transcriptomeand experimental data, we identified potential genes and regulatory elements related to such terrestrial adaptation traits as pulmonary surfactant, anxiolytic ability, pentadactyl limbs, and pharyngeal remodeling. Our results provide insights and key resources for understanding the evolutionary pathway leading from fishes to humans.
- 相关文献
作者其他论文 更多>>
-
Identification of mare milk adulteration with cow milk by liquid chromatography-high resolution mass spectrometry based on proteomics and metabolomics approaches
作者：Ji, Zhongyuan;Deng, Chunxia;Du, Qijing;Wang, Jun;Fan, Rongbo;Han, Rongwei;Yang, Yongxin;Zhang, Junyu;Guo, Tongjun;Hu, Zhisheng
关键词：Adulteration; Mare milk; Data -independent acquisition; Proteomics; Metabolomics
-
Urbanization alters soil bacterial communities in southern China coastal cities
作者：Fu, Bing;Fang, Chang;Pan, Sentao;Zhou, Lei;Yan, Yumeng;Yang, Yan;He, Yinglin;Chen, Shijun;Yang, Huirong;Wang, Jun;Fu, Bing;Fang, Chang;Pan, Sentao;He, Yinglin;Chen, Shijun;Yang, Huirong;Xia, Jun;Peng, Yisheng
关键词：Urbanization; Coastal city; Soil; Bacterial community
-
A missense mutation in RRM1 contributes to animal tameness
作者：Dou, Mingle;Li, Ming;Zheng, Zhuqing;Chen, Qiuming;Wang, Jinxin;Shan, Huiquan;Wang, Fei;Dai, Xuelei;Li, Yunjia;Yang, Zhirui;Tan, Guanghui;Luo, Funong;Wu, Jiang Wei;Nanaei, Hojjat Asadollahpour;Niyazbekova, Zhannur;Wang, Xihong;Jiang, Yu;Li, Ming;Zheng, Zhuqing;Zheng, Zhuqing;Chen, Qiuming;Wu, Yongji;Zhao, Shanting;Chen, Lei;Wang, Wen;Shi, Yun Stone;Luo, Xiong-Jian;Nanaei, Hojjat Asadollahpour;Zhang, Guojie;Wang, Wen;Zheng, Wenxin;Jiang, Yu
关键词：
-
Retrospective genomic analysis of the first Lumpy skin disease virus outbreak in China (2019)
作者：Wei, Yu-Rong;Ma, Wen-Ge;Wang, Ping;Yang, Xue-Yun;Mi, Xiao-Yun;Wu, Jian-Yong;Huang, Jiong;Wang, Wen;Su, Xiao-Hui
关键词：Lumpy skin disease virus; Illumina sequencing; phylogenetic analysis; genome sequence; genome alignment
-
Genetic basis of ruminant headgear and rapid antler regeneration
作者：Wang, Yu;Wang, Nini;Zhao, Yue;Pan, Xiangyu;Zheng, Zhuqing;Dou, Mingle;Peng, Shujun;Liu, Jing;Li, Ming;Song, Chengchuang;Zhao, Chen;Jiang, Yu;Zhang, Chenzhou;Chen, Xianqing;Wang, Kun;Liu, Chang;Lin, Zeshan;Chen, Lei;Zhu, Wenbo;Wang, Wen;Qiu, Qiang;Li, Zhipeng;Li, Guangyu;Heller, Rasmus;Liu, Rong;Dai, Xueqin;Chen, Ceshi;Liu, Rong;Dai, Xueqin;Chen, Ceshi;Zhang, Guojie;Wang, Wen;Han, Jiangang;Jiang, Lin;Hao, Fei;Yang, Hui;Zheng, Chengli;Wang, Jianming;Hu, Shengwei;Li, Cunyuan;Liu, Mingjun;Sonstegard, Tad S.;Zhang, Guojie;Zhang, Guojie;Wang, Wen;Zhang, Guojie
关键词：
-
An in vitro larval migration assay for assessing anthelmintic activity of different drug classes against Ascaris suum
作者：Zhao, Jianguo;Song, Shuaibao;Han, Qian;Zhao, Jianguo;Song, Shuaibao;Han, Qian;Zhao, Jianguo;Han, Qian;Zhao, Jianguo;Cai, Jianping;Han, Qian;Williams, Andrew R.;Hansen, Tina Vicky Alstrup;Thamsborg, Stig M.;Chen, Gang;Kang, Ming;Zhang, Zhuangzhi;Liu, Qun
关键词：Parasitic nematode;Ascaris suum;Anthelmintic;Larval migration assay;Benzimidazole;Agar
