文献类型： 外文期刊

作者： Wang, Chaoxia ¹ ; Feng, Jianhua ² ; Chen, Yujiao ⁶ ; Li, Dongmei ² ; Liu, Li ⁶ ; Wu, Yuqian ⁷ ; Zhang, Shujun ³ ; Du, Simiao ⁵ ; Zhang, Yaozhou ³ ;

作者机构： 1.Tianjin Acad Agr Sci, Management Ctr Tianjin Modern Agr Sci & Technol I, Tianjin 300192, Peoples R China

2.Tianjin Lakeside Powergene Sci Dev Co Ltd, Tianjin 300309, Peoples R China

3.Tianjin Univ, Res Ctr Human Genome, Tianjin 300309, Peoples R China

4.Tianjin Int Joint Acad Biomed, Tianjin 300457, Peoples R China

5.Zheng Yuan Tang Tianjin Biotechnol Co Ltd, Tianjin 300457, Peoples R China

6.Tuke Tianjing Pharmaceut Technol Co Ltd, Tianjin 300457, Peoples R China

7.Guian Precis Med Acad Co Ltd, Guian 550029, Guizhou, Peoples R China

关键词： Beauveria bassiana; Cordyceps militaris; Ophiocordyceps sinensis; Mitogenome; DNA methylation; RNA editing

期刊名称：MITOCHONDRION （ 影响因子：4.16； 五年影响因子：4.245 ）

ISSN： 1567-7249

年卷期： 2020 年 51 卷

页码：

收录情况： SCI

摘要： Beauveria bassiana, Cordyceps militaris and Ophiocordyceps sinensis (Ascomycotina) are traditional Chinese medicines. Here, mitogenomes of these three Ascomycotina fungi were sequenced and de-novo assembled using single-molecule real-time sequencing. The results showed that their complete mitogenomes were 31,258, 31,854 and 157,584 bp, respectively, with sequencing depth approximately 278,760 x, 326,283 x and 69,385 x. Types of repeat sequences were mainly (AA)n, (AAT)n, (TA)n and (TATT)n. DNA methylation motifs were revealed in DNA modifications of these three fungi. We discovered new models of RNA editing through analysis of transcriptomes from B. bassiana and C. militaris. These data lay a solid foundation for further genetic and biological studies about these three fungi, especially for elucidating the mitogenome evolution and exploring the regulatory mechanism of adapting environment.